Central nervous system reactions to methotrexate have been reported, especially when given via the intrathecal route (directly methotrexate into the cerebrospinal fluid), which include myelopathies and leucoencephalopathies . It has a variety of cutaneous side effects, particularly can you drink while taking methotrexate methotrexate and alcohol interaction methotrexate allergic when administered in high doses .
Methotrexate has also been methotrexate used for multiple sclerosis .
People with cancer who receive the medication often methotrexate nickname these effects “chemo brain” or “chemo fog” .  Neurotoxicity may result from methotrexate the drug crossing the blood�brain barrier and damaging neurons in the cerebral cortex . Another little understood but serious possible adverse methotrexate 10 mg tablets side effects methotrexate contraindications when is the best time to take effect of methotrexate is neurological damage and memory loss .
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